QPRT purified MaxPab mouse polyclonal antibody (B02P)
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More Files
- More Functions
Western Blot (Tissue lysate)
QPRT MaxPab polyclonal antibody. Western Blot analysis of QPRT expression in human liver.
Western Blot (Tissue lysate)
QPRT MaxPab polyclonal antibody. Western Blot analysis of QPRT expression in human placenta.
Western Blot (Transfected lysate)
Western Blot analysis of QPRT expression in transfected 293T cell line (H00023475-T01) by QPRT MaxPab polyclonal antibody.
Lane 1: QPRT transfected lysate(32.67 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human QPRT protein.
Immunogen
QPRT (-, 1 a.a. ~ 297 a.a) full-length human protein.
Sequence
MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGILAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFALKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPKIH
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84); Rat (82)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
QPRT MaxPab polyclonal antibody. Western Blot analysis of QPRT expression in human liver.Western Blot (Tissue lysate)
QPRT MaxPab polyclonal antibody. Western Blot analysis of QPRT expression in human placenta.Western Blot (Transfected lysate)
Western Blot analysis of QPRT expression in transfected 293T cell line (H00023475-T01) by QPRT MaxPab polyclonal antibody.
Lane 1: QPRT transfected lysate(32.67 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — QPRT
Entrez GeneID
23475GeneBank Accession#
BC005060.1Protein Accession#
-Gene Name
QPRT
Gene Alias
QPRTase
Gene Description
quinolinate phosphoribosyltransferase
Omim ID
606248Gene Ontology
HyperlinkGene Summary
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq
Other Designations
nicotinate-nucleotide pyrophosphorylase (carboxylating)
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Interactome
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Pathway
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