CUGBP1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human CUGBP1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human CUGBP1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human CUGBP1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — CUGBP1
Entrez GeneID
10658GeneBank Accession#
CUGBP1Gene Name
CUGBP1
Gene Alias
BRUNOL2, CUG-BP, CUGBP, NAB50, hNab50
Gene Description
CUG triplet repeat, RNA binding protein 1
Omim ID
601074Gene Ontology
HyperlinkGene Summary
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
CUG RNA-binding protein|CUG triplet repeat, RNA-binding protein 1|bruno-like 2|nuclear polyadenylated RNA-binding protein, 50-kD
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Interactome
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+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
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