TRIM21 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant TRIM21.
Immunogen
TRIM21 (NP_003132, 68 a.a. ~ 175 a.a) partial recombinant protein with GST tag.
Sequence
QLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQK
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.99 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
TRIM21 polyclonal antibody (A01), Lot # 051108JC01 Western Blot analysis of TRIM21 expression in Y-79 ( Cat # L042V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — TRIM21
Entrez GeneID
6737GeneBank Accession#
NM_003141Protein Accession#
NP_003132Gene Name
TRIM21
Gene Alias
RNF81, RO52, SSA, SSA1
Gene Description
tripartite motif-containing 21
Omim ID
109092Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq
Other Designations
Sicca syndrome antigen A|Sjogren syndrome antigen A1 (52kDa, ribonucleoprotein autoantigen SS-A/Ro)|tripartite motif protein 21
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Interactome
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Disease
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