HLA-DOB polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (36.01 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant HLA-DOB.
Immunogen
HLA-DOB (NP_002111, 27 a.a. ~ 116 a.a) partial recombinant protein with GST tag.
Sequence
TDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDSDVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFT
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.01 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — HLA-DOB
Entrez GeneID
3112GeneBank Accession#
NM_002120Protein Accession#
NP_002111Gene Name
HLA-DOB
Gene Alias
DOB
Gene Description
major histocompatibility complex, class II, DO beta
Omim ID
600629Gene Ontology
HyperlinkGene Summary
HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq
Other Designations
HLA class II histocompatibility antigen, DO beta chain|OTTHUMP00000029312|class II beta chain
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Interactome
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Pathway
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Disease
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