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BIOtech
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HLA-DMA (Human) IP-WB Antibody Pair

  • Catalog # : H00003108-PW1
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00003108-PW1
    Immunoprecipitation of HLA-DMA transfected lysate using rabbit polyclonal anti-HLA-DMA and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-HLA-DMA.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-HLA-DMA (300 ul)
    2. Antibody pair for WB: mouse polyclonal anti-HLA-DMA (50 ul)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Entrez GeneID:
  • 3108
  • Gene Name:
  • HLA-DMA
  • Gene Alias:
  • D6S222E,DMA,HLADM,RING6
  • Gene Description:
  • major histocompatibility complex, class II, DM alpha
  • Gene Summary:
  • HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000029242,OTTHUMP00000062997,class II histocompatibility antigen, M alpha chain
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