FOSL2 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human FOSL2 protein.
Immunogen
FOSL2 (NP_005244.1, 1 a.a. ~ 326 a.a) full-length human protein.
Sequence
MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDKAQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (94)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of FOSL2 transfected lysate using anti-FOSL2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with FOSL2 purified MaxPab mouse polyclonal antibody (B01P) (H00002355-B01P). -
Gene Info — FOSL2
Entrez GeneID
2355GeneBank Accession#
NM_005253.3Protein Accession#
NP_005244.1Gene Name
FOSL2
Gene Alias
FLJ23306, FRA2
Gene Description
FOS-like antigen 2
Omim ID
601575Gene Ontology
HyperlinkGene Summary
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq
Other Designations
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Interactome
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Disease
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Publication Reference
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FOSL2 promotes leptin gene expression in human and mouse adipocytes.
Wrann CD, Eguchi J, Bozec A, Xu Z, Mikkelsen T, Gimble J, Nave H, Wagner EF, Ong SE, Rosen ED.
The Journal of Clinical Investigation 2012 Mar; 122(3):1010.
Application:ChIP-Seq, ChIP-qPCR, Human, adipocytes.
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FOSL2 promotes leptin gene expression in human and mouse adipocytes.
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