Immunoprecipitation of CSF3R transfected lysate using anti-CSF3R MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with CSF3R purified MaxPab mouse polyclonal antibody (B01P) (H00001441-B01P).
The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, with three of the isoforms being membrane-bound and the other being secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq