ASCL1 monoclonal antibody (M03), clone 3D3
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More Files
- More Functions
Western Blot (Cell lysate)
ASCL1 monoclonal antibody (M03), clone 3D3 Western Blot analysis of ASCL1 expression in C32 ( Cat # L002V1 ).
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ASCL1 is approximately 1ng/ml as a capture antibody.
Western Blot detection against Immunogen (36.74 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ASCL1.
Immunogen
ASCL1 (NP_004307, 137 a.a. ~ 236 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSNDLNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ASCL1 monoclonal antibody (M03), clone 3D3 Western Blot analysis of ASCL1 expression in C32 ( Cat # L002V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ASCL1 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — ASCL1
Entrez GeneID
429GeneBank Accession#
NM_004316Protein Accession#
NP_004307Gene Name
ASCL1
Gene Alias
ASH1, HASH1, MASH1, bHLHa46
Gene Description
achaete-scute complex homolog 1 (Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq
Other Designations
achaete scute protein|achaete-scute complex homolog 1|achaete-scute complex-like 1
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Interactome
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Disease
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