AGER monoclonal antibody (M02), clone 1C1
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More Files
- More Functions
Western Blot (Tissue lysate)
AGER monoclonal antibody (M02), clone 1C1. Western Blot analysis of AGER expression in human kidney.
Western Blot (Transfected lysate)
Western Blot analysis of AGER expression in transfected 293T cell line by AGER monoclonal antibody (M02), clone 1C1.
Lane 1: AGER transfected lysate(42.8 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of AGER transfected lysate using anti-AGER monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with AGER MaxPab rabbit polyclonal antibody.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged AGER is approximately 0.3ng/ml as a capture antibody.
Western Blot detection against Immunogen (67.76 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant AGER.
Immunogen
AGER (AAH20669.1, 23 a.a. ~ 404 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
AQNITARIGEPLVLKCKGAPKKPPQRLEWNLNTGRTEAWKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQIPGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQLVVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYSCVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGVILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (78); Rat (79)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (67.76 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
AGER monoclonal antibody (M02), clone 1C1. Western Blot analysis of AGER expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of AGER expression in transfected 293T cell line by AGER monoclonal antibody (M02), clone 1C1.
Lane 1: AGER transfected lysate(42.8 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Immunoprecipitation
Immunoprecipitation of AGER transfected lysate using anti-AGER monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with AGER MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged AGER is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — AGER
Entrez GeneID
177GeneBank Accession#
BC020669Protein Accession#
AAH20669.1Gene Name
AGER
Gene Alias
MGC22357, RAGE
Gene Description
advanced glycosylation end product-specific receptor
Omim ID
600214Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000029155|OTTHUMP00000029156|advanced glycosylation end product-specific receptor RAGE3|advanced glycosylation end product-specific receptor variant sRAGE1|advanced glycosylation end product-specific receptor variant sRAGE2|receptor for advanced
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Interactome
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Disease
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