DNMT1 monoclonal antibody, clone 4G11-C7 (ATTO 488)
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More Files
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This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Application Data with Unconjugated Antibody
Western Blot (Cell lysate)
Western blot analysis of Jurkat lysates with DNMT1 monoclonal antibody, clone 4G11-C7 (Cat # MAB11764) at 1:100 dilution.
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Specifications
Product Description
Mouse monoclonal antibody raised against partial recombinant DNMT1.
Immunogen
Recombinant protein corresponding to amino acids of 620-950 of human DNMT1.
Host
Mouse
Reactivity
Human, Mouse, Zebra fish
Specificity
The antibody will cross-react with mouse DNMT1.
Form
Liquid
Conjugation
ATTO 488
Extinction Coefficient
90,000
Excitation (Max)
501 nm
Emission (Max)
523 nm
Purification
Protein G Purification
Isotype
IgG1 Kappa
Recommend Usage
Immunohistochemistry (1:1000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Application Data with Unconjugated AntibodyWestern Blot (Cell lysate)
Western blot analysis of Jurkat lysates with DNMT1 monoclonal antibody, clone 4G11-C7 (Cat # MAB11764) at 1:100 dilution.
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Applications
ChIP
Western Blot (Cell lysate)
Immunohistochemistry
Immunoprecipitation
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Gene Info — DNMT1
Entrez GeneID
1786Protein Accession#
NP_001370Gene Name
DNMT1
Gene Alias
AIM, CXXC9, DNMT, FLJ16293, MCMT, MGC104992
Gene Description
DNA (cytosine-5-)-methyltransferase 1
Omim ID
126375Gene Ontology
HyperlinkGene Summary
DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CXXC finger protein 9|DNA methyltransferase 1
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Interactomes
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Pathways
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Diseases
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