Thyroid Peroxidase IgG ELISA Kit
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Specifications
Product Description
Thyroid Peroxidase IgG ELISA Kit is used for the detection of IgG antibody to thyroid peroxidase in human serum or plasma.
Suitable Sample
Plasma, Serum
Sample Volume
100 uL (diluted)
Label
HRP-conjugate
Detection Method
Colorimetric
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store the kit at 4°C.
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Applications
Qualitative
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Gene Info — TPO
Entrez GeneID
7173Gene Name
TPO
Gene Alias
MSA, TPX
Gene Description
thyroid peroxidase
Gene Ontology
HyperlinkGene Summary
This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional splice variants have been described but their biological natures have not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000115304|OTTHUMP00000115536|thyroid microsomal antigen|thyroperoxidase
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Pathways
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Diseases
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Publication Reference
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WITHDRAWN: A female autoimmunity gene exists: DDX3X.
Dillon SP, Kurien BT, Maier-Moore JS, Wiley GB, Gaffney PM, Scofield RH.
Medical Hypotheses 2012 Aug; [Epub].
Application:Quant, Human, DNA samples from patients with systemic lupus erythematosus.
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WITHDRAWN: A female autoimmunity gene exists: DDX3X.
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