Products

Immunohistochemistry

Immunohistochemical staining of human pancreatic tissue with Histone H1.4 (phospho T17) recombinant monoclonal antibody, clone 3E1 (Cat # RAB04185) (diluated at 1:100).

Immunohistochemistry

Immunohistochemical staining of human lymph node tissue with Histone H1.4 (phospho T17) recombinant monoclonal antibody, clone 3E1 (Cat # RAB04185) (diluated at 1:100).

Immunofluorescence

Immunofluorescent staining of MCF-7 cells with Histone H1.4 (phospho T17) recombinant monoclonal antibody, clone 3E1 (Cat # RAB04185) (diluated at 1:56). The secondary antibody was Alexa Fluor 488-congugated goat anti-rabbit IgG (green). Counter-stain DAPI was used (blue).

Enzyme-linked Immunoabsorbent Assay

Entrez GeneID

3008

Protein Accession#

P10412

Gene Name

HIST1H1E

Gene Alias

H1.4, H1F4, MGC116819, dJ221C16.5

Gene Description

histone cluster 1, H1e

Omim ID

142220

Gene Ontology

Hyperlink

Gene Summary

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq

Other Designations

H1 histone family, member 4|histone 1, H1e|histone H1b