GABRA1 recombinant monoclonal antibody, clone 1F4
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Specification
Product Description
Mouse recombinant monoclonal antibody raised against human GABRA1.
Antibody Species
Mouse
Immunogen
Original antibody is raised against alpha1beta2gamma2 GABA-A receptor.
Reactivity
Human
Form
Liquid
Isotype
IgG2b kappa
Recommend Usage
Crystallography
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS with 0.02% Proclin 300
Storage Instruction
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Crystallography
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Gene Info — GABRA1
Entrez GeneID
2554Gene Name
GABRA1
Gene Alias
ECA4, EJM
Gene Description
gamma-aminobutyric acid (GABA) A receptor, alpha 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000160870
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