POT1 recombinant monoclonal antibody, clone R06-9I1
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: K562, Lane 2: C6 and Lane 3: 3T3 lysates with POT1 recombinant monoclonal antibody, clone R06-9I1 (Cat # RAB01988).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human POT1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human POT1.
Theoretical MW (kDa)
Calculated MW: 71 kD
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: K562, Lane 2: C6 and Lane 3: 3T3 lysates with POT1 recombinant monoclonal antibody, clone R06-9I1 (Cat # RAB01988). -
Gene Info — POT1
Entrez GeneID
25913Protein Accession#
Q9NUX5Gene Name
POT1
Gene Alias
DKFZp586D211, hPot1
Gene Description
POT1 protection of telomeres 1 homolog (S. pombe)
Omim ID
606478Gene Ontology
HyperlinkGene Summary
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
POT1-like telomere end-binding protein|protection of telomeres 1
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Interactome
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Disease
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