4-1BB humanized monoclonal antibody, clone D2D
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More Files
- More Functions
Flow Cytometry
Flow cytometric analysis of human CRC CD3 T cells were treated with 4-1BB Humanized monoclonal antibody, clone D2D (Cat # RAB01123-M01J) to activated human CD3 T cells.
Western Blot (Cell lysate)
4-1BB Humanized monoclonal antibody, clone D2D. Western Blot analysis of 4-1BB expression in Jurkat.
Western Blot detection against Immunogen.
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Specification
Product Description
Humanized recombinant monoclonal antibody raised against 4-1BB.
Antibody Species
Human
Immunogen
Human 4-1BB recombinant protein
Reactivity
Human
Form
Liquid
Purification
Protein A sepharose
Isotype
Human IgG1
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen.
Storage Buffer
In PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Flow Cytometry
Flow cytometric analysis of human CRC CD3 T cells were treated with 4-1BB Humanized monoclonal antibody, clone D2D (Cat # RAB01123-M01J) to activated human CD3 T cells.Western Blot (Cell lysate)
4-1BB Humanized monoclonal antibody, clone D2D. Western Blot analysis of 4-1BB expression in Jurkat.Western Blot (Recombinant protein)
ELISA
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Gene Info — TNFRSF9
Entrez GeneID
3604Gene Name
TNFRSF9
Gene Alias
4-1BB, CD137, CDw137, ILA, MGC2172
Gene Description
tumor necrosis factor receptor superfamily, member 9
Omim ID
602250Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq
Other Designations
4-1BB ligand receptor|CD137 antigen|OTTHUMP00000001360|OTTHUMP00000044294|T cell antigen ILA|homolog of mouse 4-1BB|induced by lymphocyte activation (ILA)|interleukin-activated receptor, homolog of mouse Ly63|receptor protein 4-1BB
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Interactome
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Pathway
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Disease
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