Recombinant rabbit monoclonal antibody raised against human CD3E.
Immunogen:
Originate antibody is raised against human CD3E.
Host:
Rabbit
Reactivity:
Human
Specificity:
This antibody reacts to CD3E.
Form:
Liquid
Purification:
Protein A affinity purified
Isotype:
Rabbit IgG2b, lambda
Recommend Usage:
Flow Cytometry Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) Western Blot The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS (0.02% Proclin 300)
Storage Instruction:
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq