CDH11 humanized monoclonal antibody, clone 1A9
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More Files
- More Functions
Flow Cytometry
Flow cytometric analysis of various prostate cancer cell lines were treated with CDH11 humanized monoclonal antibody, clone 1A9 (Cat # RAB01070-M01J).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of various tissues with CDH11 humanized monoclonal antibody, clone 1A9 (Cat # RAB01070-M01J)
( Left ) Breast tumor
( Right ) Prostate tumor
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Specification
Product Description
Humanized recombinant monoclonal antibody raised against CDH11.
Antibody Species
Human
Immunogen
CDH11 recombinant protein
Reactivity
Human
Form
Liquid
Purification
Protein A sepharose
Isotype
Human IgG1
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In PBS, pH 7.4
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Flow Cytometry
Flow cytometric analysis of various prostate cancer cell lines were treated with CDH11 humanized monoclonal antibody, clone 1A9 (Cat # RAB01070-M01J).Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of various tissues with CDH11 humanized monoclonal antibody, clone 1A9 (Cat # RAB01070-M01J)
( Left ) Breast tumor
( Right ) Prostate tumor
ELISA
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Gene Info — CDH11
Entrez GeneID
1009Gene Name
CDH11
Gene Alias
CAD11, CDHOB, OB, OSF-4
Gene Description
cadherin 11, type 2, OB-cadherin (osteoblast)
Omim ID
600023Gene Ontology
HyperlinkGene Summary
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq
Other Designations
OB-cadherin|cadherin 11, type 2|cadherin-11|osteoblast cadherin
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Interactome
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Disease
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