Recombinant human monoclonal antibody raised against CD3 (LALAPG mutations in Fc fragments).
Immunogen:
Human CD3E & CD3D Heterodimer Proteins.
Reactivity:
Human
Specificity:
This antibody recognizes human CD3.
Form:
Liquid
Purification:
Protein A sepharose
Isotype:
Human IgG1 LALAPG mutations in Fc fragments.
Storage Buffer:
In PBS, pH 7.4.
Storage Instruction:
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Antibody Species:
Human
Applications
Flow Cytometry
Flow cytometry (transfected cell) analysis of human CD3 T cells were treated with CD3 recombinant human monoclonal antibody, clone H2L2 (Cat # RAB01069-M01J). This antibody efficiently bound to human CD3 T cells.
Surface Plasmon Resonance
Surface Plasmon Resonance analysis (Biacore Assay) with CD3 recombinant human monoclonal antibody, clone H2L2 (Cat # RAB01069-M01J).
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq