CD3 humanized monoclonal antibody, clone H2L2
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More Files
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Flow Cytometry
Flow cytometry (transfected cell) analysis of human CD3 T cells were treated with CD3 humanized monoclonal antibody, clone H2L2 (Cat # RAB01069-M01J). This antibody efficiently bound to human CD3 T cells.
Surface Plasmon Resonance
Surface Plasmon Resonance analysis (Biacore Assay) with CD3 humanized monoclonal antibody, clone H2L2 (Cat # RAB01069-M01J).
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Specification
Product Description
Humanized recombinant monoclonal antibody raised against CD3.
Antibody Species
Human
Immunogen
Human CD3E & CD3D Heterodimer Proteins.
Reactivity
Human
Specificity
This antibody recognizes human CD3.
Form
Liquid
Purification
Protein A sepharose
Isotype
Human IgG1 with LALAPG mutations in Fc fragment
Storage Buffer
In PBS, pH 7.4
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Flow Cytometry
Flow cytometry (transfected cell) analysis of human CD3 T cells were treated with CD3 humanized monoclonal antibody, clone H2L2 (Cat # RAB01069-M01J). This antibody efficiently bound to human CD3 T cells.Surface Plasmon Resonance
Surface Plasmon Resonance analysis (Biacore Assay) with CD3 humanized monoclonal antibody, clone H2L2 (Cat # RAB01069-M01J). -
Gene Info — CD3D
Entrez GeneID
915GeneBank Accession#
NM_000732.4Protein Accession#
NP_000723.1Gene Name
CD3D
Gene Alias
CD3-DELTA, T3D
Gene Description
CD3d molecule, delta (CD3-TCR complex)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq
Other Designations
CD3D antigen, delta polypeptide|CD3d antigen, delta polypeptide (TiT3 complex)|T-cell receptor T3 delta chain|T-cell surface glycoprotein CD3 delta chain
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Interactome
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Pathway
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Disease
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