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HLA-DP recombinant monoclonal antibody, clone HLA-Pan/2967R 

  • Catalog # : RAB00686
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Recombinant rabbit monoclonal antibody raised against human HLA-DP.
  • Immunogen:
  • Non-T, non-B human acute lymphoblastic leukemia REH6 cell line.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • ELISA (2-5 ug/mL for coating)
    Flow Cytometry (1-2 ug/million cells)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
    Immunofluorescence (1-2 ug/mL)
    Western Blot (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 1 mg/mL PBS.
  • Storage Instruction:
  • Store at -20 to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot (cell lysate) analysis of Ramos cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human tonsil.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of Ramos cells. This antibody followed by Goat anti-rabbit IgG-CF488 (Green). Isotype control (Red).
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of Raji cells. This antibody followed by Goat anti-rabbit IgG-CF488 (Green). Nuclei stained with Reddot (Red).
  • Enzyme-linked Immunoabsorbent Assay
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of Raji cells. This antibody followed by goat anti-mouse IgG-CF488 (Blue). Isotype Control (Red).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Enzyme-linked Immunoabsorbent Assay
  • Gene Information
  • Entrez GeneID:
  • 3115
  • Protein Accession#:
  • P04440; P01908; P01909; P01920; P01903
  • Gene Name:
  • HLA-DPB1
  • Gene Alias:
  • DPB1,HLA-DP1B
  • Gene Description:
  • major histocompatibility complex, class II, DP beta 1
  • Gene Summary:
  • HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq
  • Other Designations:
  • HLA DP14-beta chain,HLA-DP histocompatibility type, beta-1 subunit,MHC HLA DPB1,MHC class II HLA-DP-beta,MHC class II HLA-DP-beta-1,MHC class II HLA-DRB1,MHC class II antigen DP beta 1 chain,MHC class II antigen DPbeta1,MHC class II antigen beta chain,OTT
  • Gene Information
  • Entrez GeneID:
  • 3117
  • Protein Accession#:
  • P04440; P01908; P01909; P01920; P01903
  • Gene Name:
  • HLA-DQA1
  • Gene Alias:
  • CD,CELIAC1,DQ-A1,FLJ27088,FLJ27328,GSE,HLA-DQA,MGC149527
  • Gene Description:
  • major histocompatibility complex, class II, DQ alpha 1
  • Gene Summary:
  • HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq
  • Other Designations:
  • Gluten-sensitive enteropathy (celiac disease),MHC HLA-DQ alpha,MHC class II HLA-D alpha glycoprotein,MHC class II HLA-DQ-alpha-1,MHC class II antigen,MHC class II surface glycoprotein,OTTHUMP00000029141,OTTHUMP00000176885,OTTHUMP00000178551,OTTHUMP0000017
  • Gene Information
  • Entrez GeneID:
  • 3122
  • Protein Accession#:
  • P04440; P01908; P01909; P01920; P01903
  • Gene Name:
  • HLA-DRA
  • Gene Alias:
  • HLA-DRA1
  • Gene Description:
  • major histocompatibility complex, class II, DR alpha
  • Gene Summary:
  • HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq
  • Other Designations:
  • HLA class II histocompatibility antigen, DR alpha chain,MHC cell surface glycoprotein,histocompatibility antigen HLA-DR alpha
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