MVP recombinant monoclonal antibody, clone VP2897R
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against full length human MVP.
Antibody Species
Rabbit
Immunogen
Recombinant protein corresponding to full-length human MVP.
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1 mg/mL PBS
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human breast carcinoma. -
Gene Info — MVP
Entrez GeneID
9961Protein Accession#
Q14764Gene Name
MVP
Gene Alias
LRP, VAULT1
Gene Description
major vault protein
Omim ID
605088Gene Ontology
HyperlinkGene Summary
This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts. [provided by RefSeq
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