TYR recombinant monoclonal antibody, clone TYR/2024R
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against full length human TYR.
Antibody Species
Rabbit
Immunogen
Recombinant protein corresponding to full-length human TYR.
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1 mg/mL PBS
Storage Instruction
Store at -20 to -80°C.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human melanoma. -
Gene Info — TYR
Entrez GeneID
7299Protein Accession#
P14679Gene Name
TYR
Gene Alias
OCA1A, OCAIA, SHEP3
Gene Description
tyrosinase (oculocutaneous albinism IA)
Gene Ontology
HyperlinkGene Summary
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq
Other Designations
tyrosinase
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Interactome
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Pathway
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Disease
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