SOX10 recombinant monoclonal antibody, clone SOX10/2311R
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against partial human SOX10.
Antibody Species
Rabbit
Immunogen
Recombinant protein corresponding to amino acids 115-269 of human SOX10.
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1 mg/mL PBS
Storage Instruction
Store at -20 to -80°C.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human melanoma. -
Gene Info — SOX10
Entrez GeneID
6663Protein Accession#
P56693Gene Name
SOX10
Gene Alias
DOM, MGC15649, WS2E, WS4
Gene Description
SRY (sex determining region Y)-box 10
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq
Other Designations
OTTHUMP00000028515|OTTHUMP00000195094|SRY-related HMG-box gene 10|dominant megacolon, mouse, human homolog of
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Interactome
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Disease
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