SOX2 recombinant monoclonal antibody, clone SOX2/3811R
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cervical carcinoma.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against partial human SOX2.
Antibody Species
Rabbit
Immunogen
Recombinant protein corresponding to amino acids 176-305 of human SOX2.
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG
Recommend Usage
ELISA (Use Ab at 2-4 ug/mL for coating)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1 mg/mL PBS
Storage Instruction
Store at -20 to -80°C.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cervical carcinoma. -
Gene Info — SOX2
Entrez GeneID
6657Protein Accession#
P48431Gene Name
SOX2
Gene Alias
ANOP3, MCOPS3, MGC2413
Gene Description
SRY (sex determining region Y)-box 2
Gene Ontology
HyperlinkGene Summary
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq
Other Designations
SRY-related HMG-box gene 2|sex-determining region Y-box 2|transcription factor SOX2
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Interactome
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Disease
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