CD207 recombinant monoclonal antibody, clone LGRN/3136R
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against partial human CD207.
Antibody Species
Rabbit
Immunogen
Recombinant protein corresponding to amino acids 74-213 of human CD207.
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG
Recommend Usage
ELISA (Use Ab at 2-4 ug/mL for coating)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1 mg/mL PBS
Storage Instruction
Store at -20 to -80°C.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — CD207
Entrez GeneID
50489Protein Accession#
Q9UJ71Gene Name
CD207
Gene Alias
CLEC4K
Gene Description
CD207 molecule, langerin
Omim ID
604862Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. [provided by RefSeq
Other Designations
C-type lectin domain family 4, member K|CD207 antigen, langerin|Langerhans cell specific c-type lectin
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