NEFL recombinant monoclonal antibody, clone NEFL/2983R
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebellum.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against full length human NEFL.
Antibody Species
Rabbit
Immunogen
Recombinant protein corresponding to full-length human NEFL.
Reactivity
Bovine, Chicken, Human, Pig, Rat
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1 mg/mL PBS
Storage Instruction
Store at -20 to -80°C.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebellum. -
Gene Info — NEFL
Entrez GeneID
4747Protein Accession#
P07196Gene Name
NEFL
Gene Alias
CMT1F, CMT2E, FLJ53642, NF-L, NF68, NFL
Gene Description
neurofilament, light polypeptide
Gene Ontology
HyperlinkGene Summary
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq
Other Designations
light molecular weight neurofilament protein|neurofilament protein, light chain|neurofilament subunit NF-L|neurofilament triplet L protein|neurofilament, light polypeptide 68kDa|neurofilament-light
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Interactome
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Pathway
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Disease
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