INSR recombinant monoclonal antibody, clone INSR/2277R
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against partial recombinant human INSR.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to extracellular domain of human INSR.
Theoretical MW (kDa)
135
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human placenta with INSR recombinant monoclonal antibody, clone INSR/2277R (Cat # RAB00500). -
Gene Info — INSR
Entrez GeneID
3643Protein Accession#
P06213Gene Name
INSR
Gene Alias
CD220, HHF5
Gene Description
insulin receptor
Gene Ontology
HyperlinkGene Summary
After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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