CDX2 recombinant monoclonal antibody, clone CDX2/2951R
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against partial recombinant human CDX2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to amino acids 150-249 of human CDX2.
Theoretical MW (kDa)
40
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon carcinoma with CDX2 recombinant monoclonal antibody, clone CDX2/2951R (Cat # RAB00465). -
Gene Info — CDX2
Entrez GeneID
1045Protein Accession#
Q99626Gene Name
CDX2
Gene Alias
CDX-3, CDX3
Gene Description
caudal type homeobox 2
Omim ID
600297Gene Ontology
HyperlinkGene Summary
The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription (German et al., 1994 [PubMed 7698771]).[supplied by OMIM
Other Designations
OTTHUMP00000018176|caudal type homeo box transcription factor 2|caudal type homeobox transcription factor 2
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