IL10 recombinant monoclonal antibody, clone IL10/2651R
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against full length recombinant human IL10.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human IL10.
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin-fixed) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1 mM PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 2 to 8°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human Endocervical Carcinoma using IL10 recombinant monoclonal antibody, clone IL10/2651R. -
Gene Info — IL10
Entrez GeneID
3586Protein Accession#
P22301Gene Name
IL10
Gene Alias
CSIF, IL-10, IL10A, MGC126450, MGC126451, TGIF
Gene Description
interleukin 10
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq
Other Designations
cytokine synthesis inhibitory factor
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Interactome
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