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HLA-DQ recombinant monoclonal antibody, clone HLA-DQA1/2866R 

  • Catalog # : RAB00427
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Recombinant rabbit monoclonal antibody raised against full length recombinant human HLA-DQ.
  • Immunogen:
  • Original antibody is raised against recombinant protein corresponding to full length human HLA-DQ.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • Flow Cytometry (1-2ug/106 cells)
    Immunohistochemistry (Frozen only) (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS (0.05% BSA, 0.05% sodium azide)
  • Storage Instruction:
  • Store at 2 to 8°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of human Raji cells labeling HLA-DQ with HLA-DQ recombinant monoclonal antibody, clone HLA-DQA1/2866R.
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of human Raji cells using HLA-DQ recombinant monoclonal antibody, clone HLA-DQA1/2866R.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Gene Information
  • Entrez GeneID:
  • 3117
  • Protein Accession#:
  • P01908; P01909; P01920
  • Gene Name:
  • HLA-DQA1
  • Gene Alias:
  • CD,CELIAC1,DQ-A1,FLJ27088,FLJ27328,GSE,HLA-DQA,MGC149527
  • Gene Description:
  • major histocompatibility complex, class II, DQ alpha 1
  • Gene Summary:
  • HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq
  • Other Designations:
  • Gluten-sensitive enteropathy (celiac disease),MHC HLA-DQ alpha,MHC class II HLA-D alpha glycoprotein,MHC class II HLA-DQ-alpha-1,MHC class II antigen,MHC class II surface glycoprotein,OTTHUMP00000029141,OTTHUMP00000176885,OTTHUMP00000178551,OTTHUMP0000017
  • Gene Information
  • Entrez GeneID:
  • 3118
  • Protein Accession#:
  • P01908; P01909; P01920
  • Gene Name:
  • HLA-DQA2
  • Gene Alias:
  • HLA-DXA
  • Gene Description:
  • major histocompatibility complex, class II, DQ alpha 2
  • Other Designations:
  • OTTHUMP00000029144
  • Gene Information
  • Entrez GeneID:
  • 3119
  • Protein Accession#:
  • P01908; P01909; P01920
  • Gene Name:
  • HLA-DQB1
  • Gene Alias:
  • CELIAC1,HLA-DQB,IDDM1
  • Gene Description:
  • major histocompatibility complex, class II, DQ beta 1
  • Gene Summary:
  • HLA-DQB1 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq
  • Other Designations:
  • MHC DQ beta,MHC class II DQ beta chain,MHC class II HLA-DQ beta glycoprotein,MHC class II antigen DQB1,MHC class II antigen HLA-DQ-beta-1,MHC class2 antigen,OTTHUMP00000178570,lymphocyte antigen,major histocompatibility complex class II beta
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