ELA3B recombinant monoclonal antibody, clone CELA3B/2809R
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with ELA3B recombinant monoclonal antibody, clone CELA3B/2809R (Cat # RAB00414).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human ELA3B.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to amino acids 82-238 of human ELA3B.
Theoretical MW (kDa)
~17
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with ELA3B recombinant monoclonal antibody, clone CELA3B/2809R (Cat # RAB00414). -
Gene Info — ELA3B
Entrez GeneID
23436Protein Accession#
P08861Gene Name
ELA3B
Gene Alias
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Gene Description
elastase 3B, pancreatic
Gene Ontology
HyperlinkGene Summary
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. [provided by RefSeq
Other Designations
OTTHUMP00000002837|elastase 1|elastase 3B|protease E
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