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TNFRSF8 recombinant monoclonal antibody, clone Ki-1/1747R

  • Catalog # : RAB00369
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  • Specification
  • Product Description:
  • Recombinant rabbit monoclonal antibody raised against human TNFRSF8.
  • Immunogen:
  • Original antibody is raised against recombinant protein corresponding to full length human TNFRSF8.
  • Theoretical MW (kDa):
  • 105-120
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Isotype:
  • IgG, kappa
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/106 cells)
    Immunofluorescence (1-2 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Antibody Species:
  • Rabbit
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human Hodgkin's lymphoma with TNFRSF8 recombinant monoclonal antibody, clone Ki-1/1747R (Cat # RAB00369).
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 943
  • Gene Name:
  • TNFRSF8
  • Gene Alias:
  • CD30,D1S166E,KI-1
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 8
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • CD30 antigen,CD30L receptor,Ki-1 antigen,OTTHUMP00000001783,cytokine receptor CD30,lymphocyte activation antigen CD30
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