Caldesmon, HMW recombinant monoclonal antibody, clone CALD1/1424R
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human uterus (A) and rat uterus (B) with Caldesmon, HMW recombinant monoclonal antibody, clone CALD1/1424R (Cat # RAB00359).
-
Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human Caldesmon, HMW.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human Caldesmon, HMW.
Theoretical MW (kDa)
150
Reactivity
Human, Rat
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human uterus (A) and rat uterus (B) with Caldesmon, HMW recombinant monoclonal antibody, clone CALD1/1424R (Cat # RAB00359).Immunofluorescence
Flow Cytometry
-
Gene Info — CALD1
Entrez GeneID
800Protein Accession#
Q05682Gene Name
CALD1
Gene Alias
CDM, H-CAD, L-CAD, MGC21352, NAG22
Gene Description
caldesmon 1
Omim ID
114213Gene Ontology
HyperlinkGene Summary
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
-
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
h-Caldesmon as a specific marker for smooth muscle tumors. Comparison with other smooth muscle markers in bone tumors.
Watanabe K, Tajino T, Sekiguchi M, Suzuki T.
American Journal of Clinical Pathology 2000 May; 113(5):663.
-
Phenotypic changes of human smooth muscle cells during development: late expression of heavy caldesmon and calponin.
Frid MG, Shekhonin BV, Koteliansky VE, Glukhova MA.
Developmental Biology 1992 Oct; 153(2):185.
-
h-Caldesmon as a specific marker for smooth muscle tumors. Comparison with other smooth muscle markers in bone tumors.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com