PDCD1 recombinant monoclonal antibody, clone PDCD1/1410R
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human PDCD1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human PDCD1.
Theoretical MW (kDa)
55
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with PDCD1 recombinant monoclonal antibody, clone PDCD1/1410R (Cat # RAB00344).Immunofluorescence
Flow Cytometry
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Gene Info — PDCD1
Entrez GeneID
5133Protein Accession#
Q15116Gene Name
PDCD1
Gene Alias
CD279, PD1, SLEB2, hPD-1, hPD-l
Gene Description
programmed cell death 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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Publication Reference
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Expression of two markers of germinal center T cells (SAP and PD-1) in angioimmunoblastic T-cell lymphoma.
Roncador G, García Verdes-Montenegro JF, Tedoldi S, Paterson JC, Klapper W, Ballabio E, Maestre L, Pileri S, Hansmann ML, Piris MA, Mason DY, Marafioti T.
Haematologica 2007 Aug; 92(8):1059.
Application:IF, IHC-P, WB-Ce, Human, Human lymphoma biopsies, Spleens, Thymus, Tonsil, YT cells.
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Expression of two markers of germinal center T cells (SAP and PD-1) in angioimmunoblastic T-cell lymphoma.
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