CDH16 recombinant monoclonal antibody, clone CDH16/1532R
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human CDH16.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human CDH16.
Theoretical MW (kDa)
130
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Protein A purification
Isotype
IgG, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/million cells)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA and 0.05% azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of (A) human renal cell carcinoma (B) rat kidney and (C) mouse kidney with CDH16 recombinant monoclonal antibody, clone CDH16/1532R (Cat # RAB00315).Immunofluorescence
Flow Cytometry
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Gene Info — CDH16
Entrez GeneID
1014Protein Accession#
O75309Gene Name
CDH16
Gene Alias
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Gene Description
cadherin 16, KSP-cadherin
Omim ID
603118Gene Ontology
HyperlinkGene Summary
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. [provided by RefSeq
Other Designations
KSP-cadherin|cadherin 16|kidney-specific cadherin
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Interactome
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Publication Reference
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Kidney-specific cadherin, a specific marker for the distal portion of the nephron and related renal neoplasms.
Shen SS, Krishna B, Chirala R, Amato RJ, Truong LD.
Modern Pathology 2005 Jul; 18(7):933.
Application:IHC-P, Human, Human renal neoplasms.
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Expression of kidney-specific cadherin distinguishes chromophobe renal cell carcinoma from renal oncocytoma.
Mazal PR, Exner M, Haitel A, Krieger S, Thomson RB, Aronson PS, Susani M.
Human Pathology 2005 Jan; 36(1):22.
Application:IHC-P, WB-Ti, Human, Chromophobe renal cell carcinoma, Renal oncocytoma.
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Kidney-specific cadherin, a specific marker for the distal portion of the nephron and related renal neoplasms.
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