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MUC1 recombinant monoclonal antibody, clone rMUC1/960

  • Catalog # : RAB00308
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  • Specification
  • Product Description:
  • Recombinant mouse monoclonal antibody raised against human MUC1.
  • Immunogen:
  • Human milk-fat globule membranes (HMFGM).
  • Theoretical MW (kDa):
  • 265-400
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia.
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG2b, kappa
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/million cells)
    Immunofluorescence (1-2 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS.
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Antibody Species:
  • Mouse
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human ovarian carcinoma with MUC1 recombinant monoclonal antibody, clone rMUC1/960 (Cat # RAB00308).
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 4582
  • Gene Name:
  • MUC1
  • Gene Alias:
  • CD227,EMA,H23AG,MAM6,PEM,PEMT,PUM
  • Gene Description:
  • mucin 1, cell surface associated
  • Gene Summary:
  • This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq
  • Other Designations:
  • DF3 antigen,H23 antigen,MUC-1/SEC,MUC-1/X,MUC1/ZD,OTTHUMP00000033787,OTTHUMP00000033790,OTTHUMP00000033795,breast carcinoma-associated antigen DF3,episialin,mucin 1,mucin 1, transmembrane,peanut-reactive urinary mucin,polymorphic epithelial mucin,tumor as
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