EPCAM recombinant monoclonal antibody, clone rVU-1D9
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon carcinoma with EPCAM recombinant monoclonal antibody, clone rVU-1D9 (Cat # RAB00306).
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Specification
Product Description
Mouse recombinant monoclonal antibody raised against human EPCAM.
Antibody Species
Mouse
Immunogen
Small cell lung carcinoma cells
Theoretical MW (kDa)
40-43
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/million cells)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon carcinoma with EPCAM recombinant monoclonal antibody, clone rVU-1D9 (Cat # RAB00306).Immunofluorescence
Flow Cytometry
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Gene Info — EPCAM
Entrez GeneID
4072Protein Accession#
P16422Gene Name
EPCAM
Gene Alias
17-1A, 323/A3, CD326, CO-17A, CO17-1A, EGP, EGP-2, EGP34, EGP40, ESA, Ep-CAM, GA733-2, HEA125, KS1/4, KSA, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1, hEGP-2
Gene Description
epithelial cell adhesion molecule
Omim ID
185535Gene Ontology
HyperlinkGene Summary
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq
Other Designations
adenocarcinoma-associated antigen|carcinoma-associated antigen GA733-2|human epithelial glycoprotein-2|membrane component, chromosome 4, surface marker (35kD glycoprotein)|tumor-associated calcium signal transducer 1
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Interactome
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Disease
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Publication Reference
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Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule.
Litvinov SV, Velders MP, Bakker HA, Fleuren GJ, Warnaar SO.
The Journal of Cell Biology 1994 Apr; 125(2):437.
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Immunohistochemical demonstration of breast-derived and/or carcinoma-associated glycoproteins in normal skin appendages and their tumors.
Tsubura A, Senzaki H, Sasaki M, Hilgers J, Morii S.
Journal of Cutaneous Pathology 1992 Feb; 19(1):73.
Application：IHC-P, Human, Skin.
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Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule.
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