TYRP1 recombinant monoclonal antibody, clone TYRP1/1564R
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human melanoma with TYRP1 recombinant monoclonal antibody, clone TYRP1/1564R (Cat # RAB00290).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human TYRP1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human TYRP1.
Reactivity
Human
Specificity
Reacts with a 75kDa melanocyte-specific gene product which identified as TYRP1.
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/million cells)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human melanoma with TYRP1 recombinant monoclonal antibody, clone TYRP1/1564R (Cat # RAB00290).Immunofluorescence
Flow Cytometry
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Gene Info — TYRP1
Entrez GeneID
7306Protein Accession#
P17643Gene Name
TYRP1
Gene Alias
CAS2, CATB, GP75, TRP, TYRP, b-PROTEIN
Gene Description
tyrosinase-related protein 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. [provided by RefSeq
Other Designations
associated with iris pigmentation
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Interactome
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Pathway
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Disease
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Publication Reference
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High-molecular-weight forms of tyrosinase and the tyrosinase-related proteins: evidence for a melanogenic complex.
Orlow SJ, Zhou BK, Chakraborty AK, Drucker M, Pifko-Hirst S, Pawelek JM.
The Journal of Investigative Dermatology 1994 Aug; 103(2):196.
Application：IP, WB-Ce, WB-Re, Mouse, Melan-a cells, Purified protein.
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High-molecular-weight forms of tyrosinase and the tyrosinase-related proteins: evidence for a melanogenic complex.
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