Fcgr3/Fcgr2b recombinant monoclonal antibody, clone 2.4G2
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Specification
Product Description
Recombinant rat monoclonal antibody raised against mouse Fcgr3/Fcgr2b.
Antibody Species
Rat
Immunogen
Original antibody is raised against mouse BALB/c macrophage J774 cell line.
Reactivity
Mouse
Specificity
This antibody binds to an epitope on the extracellular domains of the mouse Fc gamma III and Fc gamma II receptors, thereby inhibiting their ability to bind antibodies via their Fc region. Also binding the Fc gamma I receptor (CD64) via its Fc domain.
Form
Liquid
Purification
Protein A affinity purification
Isotype
IgG2b, kappa
Recommend Usage
Blocking
Flow Cytometry (1 ug/mL)
Immunofluorescence
Immunohistochemistry (5 ug/mL)
Immunoprecipitation (10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.02% Proclin 300).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry
Immunofluorescence
Immunoprecipitation
Blocking
Flow Cytometry
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Gene Info — Fcgr2b
Entrez GeneID
14130Protein Accession#
P08508;P08101Gene Name
Fcgr2b
Gene Alias
AI528646, CD32, F630109E10Rik, Fc[g]RII, FcgRII, Fcgr2, Fcgr2a, Fcr-2, Fcr-3, Ly-17, Ly-m20, LyM-1, Lym-1
Gene Description
Fc receptor, IgG, low affinity IIb
Gene Ontology
HyperlinkGene Summary
IgG
Other Designations
Fc gamma RIIB|Fc-gamma-RII|FcgammaRIIB|OTTMUSP00000024374|OTTMUSP00000024375
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Gene Info — Fcgr3
Entrez GeneID
14131Protein Accession#
P08508;P08101Gene Name
Fcgr3
Gene Alias
CD16
Gene Description
Fc receptor, IgG, low affinity III
Gene Ontology
HyperlinkGene Summary
IgG
Other Designations
Fc gamma receptor III|Fcg receptor III|FcgammaRIII
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