Recombinant rabbit monoclonal antibody raised against human EGFR.
Original antibody is raised against partially purified EGFR from A431 cells.
This antibody recognizes the extracellular domain of EGFR.
Protein A affinity purification
Flow Cytometry (1 ug/mL) Immunofluorescence Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) Immunoprecipitation (10 ug/mL) Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
In PBS, pH 7.2 (0.02% Proclin 300).
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog,cell growth inhibiting protein 40,cell proliferation-inducing protein 61,epidermal growth factor receptor