CD38 recombinant monoclonal antibody, clone HB7
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human CD38.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against human BJAB cell line.
Reactivity
Human
Specificity
This antibody binds to an epitope between amino acids 273-285 of human CD38, an approximately 45 kDa type II transmembrane protein, expressed on essentially all pre-B lymphocytes, plasma cells, and thymocytes. Also present on activated T lymphocytes, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. Bimodally expressed during B cell development, modulating from high in immature cells to low in intermediate ones and back to high on mature B cells.
Form
Liquid
Purification
Protein A affinity purification
Isotype
IgG, kappa
Recommend Usage
Flow Cytometry (1 ug/mL)
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.02% Proclin 300)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Flow Cytometry
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Gene Info — CD38
Entrez GeneID
952Protein Accession#
P28907Gene Name
CD38
Gene Alias
T10
Gene Description
CD38 molecule
Omim ID
107270Gene Ontology
HyperlinkGene Summary
CD38 is a novel multifunctional ectoenzyme widely expressed in cells and tissues especially in leukocytes. CD38 also functions in cell adhesion,signal transduction and calcium signaling. [provided by RefSeq
Other Designations
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase|CD38 antigen|CD38 antigen (p45)|cyclic ADP-ribose hydrolase
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Interactome
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Pathway
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Disease
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Publication Reference
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Reversal of endothelial dysfunction by nicotinamide mononucleotide via extracellular conversion to nicotinamide riboside.
Mateuszuk Ł, Campagna R, Kutryb-Zając B, Kuś K, Słominska EM, Smolenski RT, Chlopicki S.
Biochemical Pharmacology 2020 May; 8:178.
Application：WB, Human, HAEC cells.
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Reversal of endothelial dysfunction by nicotinamide mononucleotide via extracellular conversion to nicotinamide riboside.
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