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ITGA5/ITGB1 recombinant monoclonal antibody, clone M200 (Volociximab)

  • Catalog # : RAB00088
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Recombinant rabbit monoclonal antibody raised against human ITGA5/ITGB1.
  • Immunogen:
  • Original antibody is raised against heterodimeric alpha 5 beta 1 Fc fusion protein.
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A affinity purification
  • Isotype:
  • IgG, kappa
  • Recommend Usage:
  • Blocking
    ELISA (0.1 ug/mL)
    Flow Cytometry (1 ug/mL)
    Immunofluorescence
    Immunohistochemistry (5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.02% Proclin 300).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Antibody Species:
  • Rabbit
  • Applications
  • Immunohistochemistry
  • Immunofluorescence
  • ELISA
  • Blocking
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry
  • Immunofluorescence
  • ELISA
  • Blocking
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3678
  • Protein Accession#:
  • P08648;P05556
  • Gene Name:
  • ITGA5
  • Gene Alias:
  • CD49e,FNRA,VLA5A
  • Gene Description:
  • integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
  • Gene Summary:
  • The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq
  • Other Designations:
  • fibronectin receptor, alpha subunit,integrin alpha 5,very late activation protein 5, alpha subunit
  • Gene Information
  • Entrez GeneID:
  • 3688
  • Protein Accession#:
  • P08648;P05556
  • Gene Name:
  • ITGB1
  • Gene Alias:
  • CD29,FNRB,GPIIA,MDF2,MSK12,VLA-BETA,VLAB
  • Gene Description:
  • integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
  • Gene Summary:
  • Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000019420,OTTHUMP00000046253,OTTHUMP00000063731,OTTHUMP00000063732,OTTHUMP00000063733,fibronectin receptor beta subunit,integrin VLA-4 beta subunit,integrin beta 1
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