TNFSF4 humanized monoclonal antibody, clone R4930 (Oxelumab)
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Specification
Product Description
Humanized recombinant monoclonal antibody raised against human TNFSF4.
Antibody Species
Human
Immunogen
Original antibody is raised against human TNFSF4.
Reactivity
Human
Specificity
This antibody binds to human TNFSF4.
Form
Liquid
Purification
Protein A affinity purification
Isotype
Human IgG1, kappa
Recommend Usage
Blocking
Flow Cytometry (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.02% Proclin 300)
Storage Instruction
Store at 4°C for up to 3 months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Blocking
Flow Cytometry
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Gene Info — TNFSF4
Entrez GeneID
7292Protein Accession#
P23510Gene Name
TNFSF4
Gene Alias
CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1
Gene Description
tumor necrosis factor (ligand) superfamily, member 4
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells. [provided by RefSeq
Other Designations
CD134 ligand|OTTHUMP00000032704|OX40 antigen ligand|OX40 ligand|glycoprotein 34 kd|tax-transcriptionally activated glycoprotein 1 (34kD)
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Pathway
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Disease
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