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CD40LG recombinant monoclonal antibody, clone hu5c8 (Ruplizumab)

  • Catalog # : RAB00034
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  • Specification
  • Product Description:
  • Recombinant human monoclonal antibody raised against human CD40LG.
  • Immunogen:
  • Original antibody is raised against native purified human CD40LG.
  • Reactivity:
  • Human
  • Specificity:
  • This antibody binds to CD40LG with an IC50 of 0.845 ug/mL.
  • Form:
  • Liquid
  • Purification:
  • Protein A affinity purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Blocking
    Flow Cytometry (1 ug/mL)
    Western Blot (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.02% Proclin 300).
  • Storage Instruction:
  • Store at 4°C for up to 3 months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Antibody Species:
  • Human
  • Applications
  • Western Blot
  • Blocking
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Blocking
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 959
  • Gene Name:
  • CD40LG
  • Gene Alias:
  • CD154,CD40L,HIGM1,IGM,IMD3,T-BAM,TNFSF5,TRAP,gp39,hCD40L
  • Gene Description:
  • CD40 ligand
  • Gene Summary:
  • The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq
  • Other Designations:
  • CD40 antigen ligand,OTTHUMP00000024130,T-B cell-activating molecule,TNF-related activation protein,tumor necrosis factor (ligand) superfamily member 5
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