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ITGAM recombinant monoclonal antibody, clone 107

  • Catalog # : RAB00025
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  • Specification
  • Product Description:
  • Recombinant mouse monoclonal antibody raised against human ITGAM.
  • Immunogen:
  • Original antibody is raised against recombinant protein corresponding to wild type human ITGAM.
  • Reactivity:
  • Human
  • Specificity:
  • This antibody binds to the MIDAS face of the A domain from ITGAM.
  • Form:
  • Liquid
  • Purification:
  • Protein A affinity purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • ELISA (0.1 ug/mL)
    Flow Cytometry (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.02% Proclin 300).
  • Storage Instruction:
  • Store at 4°C for up to 3 months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Antibody Species:
  • Mouse
  • Applications
  • ELISA
  • Flow Cytometry
  • Application Image
  • ELISA
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3684
  • Gene Name:
  • ITGAM
  • Gene Alias:
  • CD11B,CR3A,MAC-1,MAC1A,MGC117044,MO1A,SLEB6
  • Gene Description:
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • Gene Summary:
  • This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • antigen CD11b (p170),complement component receptor 3, alpha,integrin alpha M,macrophage antigen alpha polypeptide,neutrophil adherence receptor alpha-M subunit
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