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Last updated: 2016/10/23
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APOE polyclonal antibody

  • Catalog # : PAB9972
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against native APOE.
  • Immunogen:
  • Native purified human APOE.
  • Host:
  • Goat
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with human apoLipoprotein E and has negligible cross-reactivity with Type A-1 A-II, B, C-I, C-II, C-III and J apoLipoproteins. Non-specific cross-reaction of anti-apoLipoprotein antibodies with other human serum proteins is negligible.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Native Purified Protein.
  • Recommend Usage:
  • ELISA (1:4000-1:8000)Western Blot (1:500-1:2000)Immunohistochemistry (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 100 mM Na2B4O7, 75 mM NaCl, 5 mM EDTA, pH 8.0 (0.01% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
  • Application Image
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 348
  • Gene Name:
  • APOE
  • Gene Alias:
  • AD2,LPG,MGC1571,apoprotein
  • Gene Description:
  • apolipoprotein E
  • Gene Summary:
  • Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq
  • Other Designations:
  • apolipoprotein E3
  • Gene Pathway
  • Related Disease
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