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Last updated: 2017/12/17
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ABCB6 polyclonal antibody

  • Catalog # : PAB9926
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ABCB6.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 440-45 of human ABCB6.
  • Host:
  • Rabbit
  • Reactivity:
  • Dog, Human
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:40000-1:200000)
    Western Blot (1:1000-1:5000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot using ABCB6 polyclonal antibody (Cat # PAB9926) (right panel, lane B6) shows detectionof Flag™-tagged human ABCB6 proteinat 104 KDa and a truncated form of theprotein at 79 KDa (arrowheads).
    The antibody successfully detected ABCB6 in KB cells transfected with the ABCB6 protein.
    A lysate prepared from KB cells without a vector insert (CV lane) should no reactivity with the antibody.
    The left panel shows a similar staining pattern using an anti-Flag™ antibody asa positive control.
    The membrane was probed with the primary antibody dilutedto 1 : 1,400.
    Personal Communication, Jill Paterson, CCR-NCI, Bethesda, MD.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • ABCB6
  • Gene Alias:
  • ABC,ABC14,EST45597,FLJ22414,MTABC3,PRP,umat
  • Gene Description:
  • ATP-binding cassette, sub-family B (MDR/TAP), member 6
  • Gene Summary:
  • The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function. [provided by RefSeq
  • Other Designations:
  • ATP-binding cassette half-transporter,ATP-binding cassette, sub-family B, member 6
  • Gene Pathway
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