Dyrk1a polyclonal antibody
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Specification
Product Description
Sheep polyclonal antibody raised against partial recombinant Dyrk1a.
Immunogen
Recombinant protein corresponding to amino acids 486-763 of mouse Dyrk1a.
Host
Sheep
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Ammonium sulfate precipitation
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
Immunofluorescence (1-10 ug/mL)
Immunoprecipitation
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.08% sodium azide).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunoprecipitation
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Gene Info — Dyrk1a
Entrez GeneID
13548Gene Name
Dyrk1a
Gene Alias
2310043O08Rik, D16Ertd272e, D16Ertd493e, Dyrk, MGC150253, MGC150254, Mnbh, Mp86, mmb
Gene Description
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
Gene Ontology
HyperlinkOther Designations
dual specificity YAK1-related kinase|dual specificity tyrosine-phosphorylation-regulated kinase 1A|protein kinase minibrain homolog
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Publication Reference
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Structural and functional characteristics of Dyrk, a novel subfamily of protein kinases with dual specificity.
Becker W, Joost HG.
Progress in Nucleic acid Research and Molecular Biology 1999 Jan; 62:1.
Application:WB-Ce, WB-Tr, Human, Mammalian cells.
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Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome "critical region".
Song WJ, Sternberg LR, Kasten-Sportes C, Keuren ML, Chung SH, Slack AC, Miller DE, Glover TW, Chiang PW, Lou L, Kurnit DM.
Genomics 1996 Dec; 38(3):331.
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Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII.
Kentrup H, Becker W, Heukelbach J, Wilmes A, Schurmann A, Huppertz C, Kainulainen H, Joost HG.
The Journal of Biological Chemistry 1996 Feb; 271(7):3488.
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Structural and functional characteristics of Dyrk, a novel subfamily of protein kinases with dual specificity.
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