DEGS2 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot using DEGS2 polyclonal antibody on human kidney cell lysate at 15 ug/lane.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DEGS2.
Immunogen
A synthetic peptide corresponding to human DEGS2.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (1-5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.08% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot using DEGS2 polyclonal antibody on human kidney cell lysate at 15 ug/lane. -
Gene Info — DEGS2
Entrez GeneID
123099Gene Name
DEGS2
Gene Alias
C14orf66, DES2, FADS8
Gene Description
degenerative spermatocyte homolog 2, lipid desaturase (Drosophila)
Omim ID
610862Gene Ontology
HyperlinkGene Summary
This gene encodes a bifunctional enzyme that is involved in the biosynthesis of phytosphingolipids in human skin and in other phytosphingolipid-containing tissues. This enzyme can act as a sphingolipid delta(4)-desaturase, and also as a sphingolipid C4-hydroxylase. [provided by RefSeq
Other Designations
degenerative spermatocyte homolog 2, lipid desaturase|sphingolipid C4-hydroxylase/delta 4-desaturase|sphingolipid delta 4 desaturase/C-4 hydroxylase|sphingolipid delta(4)-desaturase/C4-hydroxylase
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Pathway
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Disease
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Publication Reference
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Dihydroceramide:sphinganine C-4-hydroxylation requires Des2 hydroxylase and the membrane form of cytochrome b5.
Enomoto A, Omae F, Miyazaki M, Kozutsumi Y, Yubisui T, Suzuki A.
The Biochemical Journal 2006 Jul; 397(2):289.
Application：IF, IHC-Fr, Mouse, Mouse small intestine.
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Identification of an essential sequence for dihydroceramide C-4 hydroxylase activity of mouse DES2.
Omae F, Miyazaki M, Enomoto A, Suzuki A.
FEBS Letters 2004 Oct; 576(1-2):63.
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DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine.
Omae F, Miyazaki M, Enomoto A, Suzuki M, Suzuki Y, Suzuki A.
The Biochemical Journal 2004 May; 379(Pt 3):687.
Application：IHC, WB, Mouse, Mouse small intestine.
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Dihydroceramide:sphinganine C-4-hydroxylation requires Des2 hydroxylase and the membrane form of cytochrome b5.
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