MARK3 polyclonal antibody
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Specification
Product Description
Sheep polyclonal antibody raised against full length recombinant MARK3.
Immunogen
Recombinant His fusion protein corresponding to full length human MARK3.
Host
Sheep
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
Western Blot (1-5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.08% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis using MARK3 polyclonal antibody on His-tagged c-tak1 (lane 1), RKO cell lysate (lane 2) and HCT-116 cell lysate (lane 3).Immunoprecipitation
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Gene Info — MARK3
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Interactome
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Disease
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Publication Reference
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The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1.
Busby EC, Leistritz DF, Abraham RT, Karnitz LM, Sarkaria JN.
Cancer Research 2000 Apr; 60(8):2108.
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C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding.
Peng CY, Graves PR, Ogg S, Thoma RS, Byrnes MJ 3rd, Wu Z, Stephenson MT, Piwnica-Worms H.
Cell Growth & Differentiation 1998 Mar; 9(3):197.
Application:IP, WB-Tr, Monkey, COS-7 cells.
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Purification of a serine kinase that associates with and phosphorylates human Cdc25C on serine 216.
Ogg S, Gabrielli B, Piwnica-Worms H.
The Journal of Biological Chemistry 1994 Dec; 269(48):30461.
Application:WB-Ce, Human, HeLa cells.
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The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1.
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