COL4A3BP polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of COL4A3BP.
Immunogen
A synthetic peptide corresponding to human COL4A3BP.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (5-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.08% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot using COL4A3BP polyclonal antibody on HT-29 cell lysate (28 ug/lane). -
Gene Info — COL4A3BP
Entrez GeneID
10087Gene Name
COL4A3BP
Gene Alias
CERT, CERTL, FLJ20597, GPBP, STARD11
Gene Description
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
Omim ID
604677Gene Ontology
HyperlinkGene Summary
This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Goodpasture antigen-binding protein|OTTHUMP00000128248|OTTHUMP00000128249|START domain containing 11|StAR-related lipid transfer (START) domain containing 11|alpha 3 type IV collagen binding protein|ceramide transporter|lipid-transfer protein CERTL
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Interactome
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Publication Reference
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Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M.
Cell 2006 Nov; 127(3):635.
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Molecular machinery for non-vesicular trafficking of ceramide.
Hanada K, Kumagai K, Yasuda S, Miura Y, Kawano M, Fukasawa M, Nishijima M.
Nature 2003 Dec; 426(6968):803.
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Goodpasture antigen-binding protein, the kinase that phosphorylates the goodpasture antigen, is an alternatively spliced variant implicated in autoimmune pathogenesis.
Raya A, Revert-Ros F, Martinez-Martinez P, Navarro S, Rosello E, Vieites B, Granero F, Forteza J, Saus J.
The Journal of Biological Chemistry 2000 Dec; 275(51):40392.
Application:IHC-P, WB, Human, Bovine, Mouse, Muscle, Renal, Skin.
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Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
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